Medical Diagnostics Articles
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The Future of Fusion Research
Ongoing efforts in nuclear fusion research promise a cheap, clean, and safe energy source for future generations. In this blog post, we’re looking at how fusion power works, its advantages, and how fusion research is bringing us closer to commercial fusion reactors. ...
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Supporting Veterinary Resilience for World Veterinary Day
April 30th is World Veterinary Day. Taking place each year on the last Saturday of April, World Veterinary Day was created in 2000 by the World Veterinary Association as an annual celebration of the veterinary profession. Each year, there is a new theme. You can read about last year’s theme here. This year, the theme is Strengthening Veterinary Resilience. ...
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Gene of the Week: SOD2 (Skin Protection)
There are around 30,000 genes in the human genome. In this weekly series, we’ll write about a new gene featured in Orig3n DNA tests so you can discover the kinds of information genetic assessments can offer you. Have you ever wondered why some people’s skin ages differently than others? There’s a gene for that™! Here at Orig3n, we’ve been dreaming of a winter ...
By Orig3n
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Leading by Example to be Intentional About Your Mind and Body
Three things that might best describe Tiago R. G. are mindful, people-oriented and non-violent. As he’s continued to expand his mind and the way he interacts with his environment, he’s also learned to make intentional choices that improve his body. This is his #Orig3nStory. ...
By Orig3n
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How Much Do You Know about Bacteriocin?
In recent years, the increase in the number of multi-drug resistant pathogens and food safety have become serious global problems, and it is increasingly important to find or develop a new generation of antibacterial drugs or preservatives. Scientists have discovered that bacteria-produced bacteriocins can control clinically relevant susceptible and resistant bacteria, and purified bacteriocins ...
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A Novel Potential Target for CAR-T Cell Therapy in Human Solid Tumors Discovered
At present, chimeric antigen receptor T cell therapy (CAR-T) has made significant achievements in the treatment of specific hematological cancers, allowing patients with relapsed/refractory disease to survive longer and become healthier, but in clinical studies, cell therapy has actually not been successful in the treatment of patients with solid tumors, in part due to the lack of tumor targets ...
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Bananas Face Another Extinction Crisis, Can Gene Editing Save Bananas?
Bananas are one of the most popular fruits in the world, however, in fact bananas are at stake and we may no longer eat them at any time. And the source of this crisis is fungal infection, and in 1950, an outbreak of a banana infectious disease with fungal infection called "Panama disease" directly led to the complete extinction of Gros Michel, the most widely planted banana variety at that ...
By Lifeasible
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Mutation-directed Neo-protein-protein Interactions in Cancer
Genetic mutations in cells are an important cause of cancer development, progression, and drug resistance. How to quickly and accurately translate massive tumor genomic information into safe and effective cancer targeted therapies in clinical practice is a scientific frontier today. At present, a large number of scientific studies have focused on how oncogenic mutations regulate the activity of ...
By Profacgen
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Enzymatic Mechanism by Which Dolphin Gut Microbes Degrade Plant Polysaccharides Unveiled
Symbiotic microbial groups within the digestive tract of herbivores are the main source of depolymerized lignocellulases. The dolphin is the largest extant rodent, usually living in the Pantanal wetland and Amazon basin, and is also known as the "king of grass" due to its diet based on grasses and aquatic plants. They can efficiently depolymerize and utilize lignocellulosic biomass through ...
By CD BioGlyco.
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Bioinformatics Analysis Brings Disease Genomics Research to a Crossroads
Introduction Since the completion of the Human Genome Project, genomics has played an increasingly critical role in the biomedical field. Its applications include variation and risk assessment in disease genomics, analysis of changes in transcriptomic gene expression, revealing epigenetic effects on tissue and organ development, and heterogeneity at the single-cell level, among others. We present ...
By CD Genomics
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Air quality monitoring equipment can be used to identify indoor pollutants
Indoor Air Quality (IAQ) IAQ (Indoor Air Quality) refers to Indoor air quality. It includes indoor air temperature, humidity, air cleanliness and fresh air volume. In the past, indoor air quality was mainly studied by temperature and humidity. This year, as a result of the introduction of air-conditioning system in modern buildings, office modernization, the popularity of household appliances and ...
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LncRNA Sequencing Helps to Find Deep Links to Disease
Long non-coding RNAs (lncRNAs) are a class of RNAs that do not code for proteins and are typically greater than 200 nucleotides in length. Studies have shown that lncRNAs are quite complex in function and play an important role in various biological processes such as development, differentiation, proliferation, metastasis, apoptosis, stem cell pluripotency, and DNA damage. Therefore, those ...
By CD Genomics
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AI Designed Mutation Resistant Broad Neutralization Antibodies Against Multiple SARS-CoV-2 Strains based on A Digital Twin of COVID-19 - Case study
Introduction The emerging variants including Delta and Omicron may not retain activity with current available mAb products that were developed during the initial outbreak with the B.l strain. In this study, we have applied AI technologies in the computational design of broad neutralization antibodies against over 1300 different historical SARS-CoV-2 strains with very small computational cost. ...
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Microbes4U - Case study
The Microbes4U® study is the first randomized double-blind placebo-controlled pilot study to evaluate the effects of pasteurized Akkermansia muciniphila administered in humans. The main objectives of the Microbes4U® study were to determine the safety, tolerance and metabolic parameters (i.e., insulin resistance, circulating lipids, visceral adiposity, body mass) after 3 months of daily ...
By A-Mansia
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The Link Between Smoking and Cognitive Decline
By now, you are likely aware of many of the well-established risks associated with smoking cigarettes, such as cancer, asthma, chronic obstructive pulmonary disease (COPD), diabetes, cardiovascular disease, and stroke. But did you know that research has discovered a link between smoking and cognitive decline? This research emphasizes the importance of identifying and controlling modifiable risk ...
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Huateng Pharma Supplies Canagliflozin Intermediates With Commercial Scale Production
Canagliflozin is a medication used to treat type 2 diabetes. It is a third-line medication to be tried after metformin, a first-line medication for type 2 diabetes. It is used together with exercise and diet. It is not recommended in type 1 diabetes. Mechanism action of Canagliflozin Canagliflozin is a sodium-glucose cotransporter (SGLT2) inhibitor. Glucose filtered in the renal tubular lumen is ...
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How does your Vaginal Microbiome Affect your Cancer Risk?
When you hear about the vaginal microbiome (VMB), your first thought may be the role it plays in stuff like yeast infections or bacterial vaginosis (BV). But with improved research, we’re uncovering more of the VMB’s long-term effects, like its role in a healthy pregnancy and delivery. The complex community of organisms living in your vagina even plays a part in your risk of ...
By Juno Bio
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What Are the Applications of Enzymes in Disease Research and Treatment?
With the development of biotechnology in the modern information age, the research, development and utilization of enzymes have become more and more in-depth, and correspondingly, the application of enzymes in medicine has become more and more extensive. 1. The relationship between enzymes and certain diseases The diseases caused by the lack of enzymes in the human body are mostly congenital or ...
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Restriction Enzymes – Molecular Scalpels
The biological function of restriction enzymes is derived from the defense of foreign DNA from invading cells. The restriction-modification system of bacteria makes the DNA bases of bacteria to be methylated and modified, so that they are not recognized and cut by their own restriction enzymes. The development of restriction endonucleases In the early 1960s, Werner Arber came up with the idea ...
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Using AI to Fight a Pandemic: Insilico Medicine Announces Novel Preclinical Candidate for COVID-19 Treatment
Insilico Medicine announced the nomination of a novel preclinical therapeutic candidate for treating COVID-19, designed using the generative chemistry AI platform Chemistry42. The new drug candidate is a 3CL protease inhibitor unique from existing drugs in its class because it can be rapidly produced. While this nomination is a potentially important development for the ongoing COVID-19 pandemic ...
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